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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
12.73
Human Site:
Y184
Identified Species:
17.5
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
Y184
V
I
P
N
S
N
F
Y
V
S
R
T
A
C
R
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
C184
V
I
P
N
S
N
F
C
V
S
R
T
A
Y
R
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
Y183
V
I
P
N
S
N
F
Y
V
S
R
T
A
Y
R
Dog
Lupus familis
XP_535848
1288
147094
Y184
V
I
P
N
S
N
F
Y
V
S
R
T
A
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
R189
Y
V
S
R
T
A
Y
R
D
S
T
S
V
Y
H
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
Q183
V
K
A
E
E
D
T
Q
F
N
Y
H
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
D102
V
C
Q
Y
Y
V
Y
D
L
Q
K
R
V
T
E
Chicken
Gallus gallus
NP_989849
1274
145838
Q205
I
L
Q
G
E
V
E
Q
I
A
M
M
K
P
K
Frog
Xenopus laevis
P50532
1290
146971
K185
Y
V
S
R
T
A
Y
K
D
N
S
S
V
Y
H
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
Y183
V
I
P
D
S
S
F
Y
V
A
R
T
A
G
K
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
K187
C
V
S
R
T
A
N
K
D
N
S
S
A
Y
Y
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
R344
T
T
A
T
S
R
M
R
M
N
A
Q
Q
R
K
Honey Bee
Apis mellifera
XP_396862
1282
148175
F183
E
I
A
K
I
L
R
F
Y
G
V
D
L
D
H
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
Q197
T
I
S
R
T
A
F
Q
N
N
S
S
S
Y
A
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
V205
V
V
P
N
S
Q
F
V
V
S
R
T
A
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
A184
I
S
L
M
K
P
K
A
Q
G
P
H
D
E
G
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
I257
D
E
E
K
P
G
L
I
I
T
R
K
A
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
86.6
93.3
93.3
N.A.
6.6
6.6
N.A.
6.6
0
0
66.6
6.6
6.6
6.6
13.3
66.6
P-Site Similarity:
100
86.6
93.3
93.3
N.A.
33.3
26.6
N.A.
26.6
33.3
33.3
93.3
33.3
26.6
13.3
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
18
0
0
24
0
6
0
12
6
0
48
0
6
% A
% Cys:
6
6
0
0
0
0
0
6
0
0
0
0
0
6
0
% C
% Asp:
6
0
0
6
0
6
0
6
18
0
0
6
6
6
0
% D
% Glu:
6
6
6
6
12
0
6
0
0
0
0
0
0
6
6
% E
% Phe:
0
0
0
0
0
0
42
6
6
0
0
0
0
6
0
% F
% Gly:
0
0
0
6
0
6
0
0
0
12
0
0
0
6
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
6
18
% H
% Ile:
12
42
0
0
6
0
0
6
12
0
0
0
0
0
0
% I
% Lys:
0
6
0
12
6
0
6
12
0
0
6
6
6
6
36
% K
% Leu:
0
6
6
0
0
6
6
0
6
0
0
0
6
0
0
% L
% Met:
0
0
0
6
0
0
6
0
6
0
6
6
0
0
0
% M
% Asn:
0
0
0
30
0
24
6
0
6
30
0
0
0
0
0
% N
% Pro:
0
0
36
0
6
6
0
0
0
0
6
0
0
6
0
% P
% Gln:
0
0
12
0
0
6
0
18
6
6
0
6
6
0
0
% Q
% Arg:
0
0
0
24
0
6
6
12
0
0
42
6
6
6
24
% R
% Ser:
0
6
24
0
42
6
0
0
0
36
18
24
6
0
0
% S
% Thr:
12
6
0
6
24
0
6
0
0
6
6
36
0
6
0
% T
% Val:
48
24
0
0
0
12
0
6
36
0
6
0
18
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
6
6
0
18
24
6
0
6
0
0
42
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _